In blond hair melanocytes in bulbs produce relatively few or incompletely melanized melanosomes. Normal anagen hair bulb lacks mhc i and ii hla expressed in aa allowing interaction of cytotoxic t cells with matrix cells.
The Histology Guide Skin
The hair follicle is a dynamic organ found in mammalian skin.
Hair bulb histology. Hair bulb hair follicle hair matrix hair papilla hair root hair shaft hypodermis internal root sheath interpapillary pegs rete pegs meissners corpuscle melanocytes of epidermis melanosomes melanin granules myoepithelial cell pacinian corpuscle papillary layer of dermis reticular layer of dermis sebaceous gland stratum basale stratum corneum. The histology of your hair can vary slightly depending your ethnicity being influenced by race and genes. It has three inner layers forming the hair shaft.
At the base of the hair folliclehair bulb there is a dermal papilla which contains the blood supply for the hair. The hair matrix which contains the proliferating cells that generate the hair and the internal root sheath is just above the dermal papilla and separated from it by a basement membrane. The hair follicle is a tubular structure with an enlarged hair bulb at its base lower left.
Explanation of hair and hair follicle structure and functions for hair follicle anatomy see more here. The pink speckled tissue lining the walls of the follicle is an ingrowth of the epidermis the outermost layer of the skin. During the growth phase an extra outer layer stratum basale appears.
From the top down the three major skin layers shown are. Histology hair bulb view related images. Alopecia areata histology.
Hair histology this image shows a histological section through the adult skin showing slices through 4 hair follicles and their associated glands in different planes. Dark brown or black hair contains large ellipsoidal markedly melanized eumelanosomes whereas red hair houses spherical pheomelanosomes. The hair shaft is the yellow structure extending from the bulb within the hair follicle.
This is a section through the hair bulb at the base of a hair follicle. The hair follicles are tubular structures having a base hair bulb that surrounds the hair papilla. The hair follicle regulates hair growth via a complex interaction between hormones neuropeptides and immune cells.
Note the purple staining keratinocytes that proliferate to form the hair as well as the wall of the follicle. In gray and white hair melanocytes in bulbs are reduced in number and melanosomes are poorly melanized. The dark column of cells in the center is the hair emerging from the dead keratinocytes.
It resides in the dermal layer of the skin and is made up of 20 different cell types each with distinct functions.
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